Japanese mushroom extract appears to last effective for the eradication of human papillomavirus (HPV), according to a airplane pilot clinical trial at The University of Texas Health Science Center at Houston (UTHealth) Medical School.
The results were presented at the 11th International Conference of the Society for Integrative Oncology inwards Houston today past times principal investigator Judith A. Smith, Pharm.D., associate professor inwards the Department of Obstetrics, Gynecology in addition to Reproductive Sciences at the UTHealth Medical School.
Ten HPV-positive women were treated orally amongst the extract, AHCC (active hexose correlated compound) in ane trial daily for upwards to half-dozen months. Five achieved a negative HPV exam final result -- 3 amongst confirmed eradication later on stopping AHCC -- amongst the remaining 2 responders continuing on the study.
Currently, at that spot is no effective medicine or supplement to process HPV, which is associated amongst to a greater extent than than 99 per centum of cervical cancer cases. According to the Centers for Disease Control in addition to Prevention, several other cancers are related to HPV, including 95 per centum of anal cancer, lx per centum of oropharyngeal, 65 per centum of vaginal cancer, l per centum of vulvar cancer in addition to 35 per centum of penile cancer.
AHCC is a readily available nutritional supplement that industrial plant to ameliorate the innate immune system. Human in addition to preclinical studies convey shown that AHCC increases the seat out and/or activeness of Natural Killer (NK) cells, dendritic cells in addition to cytokines, which assist the trunk struggle off infections in addition to block tumor growth.
"The results are really encouraging," Smith said. "We were able to cause upwards one's take away heed that at to the lowest degree 3 months of handling is necessary but approximately necessitate to extend that to half-dozen months. Since AHCC is a nutritional supplement amongst no side effects in addition to other immune modulating benefits, nosotros volition last planning on using half-dozen months of handling inwards our stage II clinical report to convey consistent report handling plan. This confirms our before preclinical research."
Smith is manager of UTHealth's Women's Health Integrative Medicine Research Team, which focuses on the rubber in addition to effective role of nutritional in addition to herbal supplements amongst pharmacologic modalities every bit it relates to women's wellness in addition to cancer.
This interrogation is proceeding to a randomized, double-blind, placebo-controlled Phase II clinical trial which has only begun at UTHealth,